HCTU is a highly efficient aminium-based coupling reagent widely utilized in solid-phase and solution-phase peptide synthesis.   Products are for research use only. Not for human use. We do not sell to patients.   HCTU is a highly efficient aminium-based coupling reagent widely utilized in solid-phase and solution-phase peptide synthesis. As a 6-chloro derivative of HBTU, HCTU exhibits superior reactivity and faster reaction kinetics, facilitating robust amide bond formation even in sterically hindered sequences with minimal racemization. HCTU reagent demonstrates excellent solubility in water or 1% acetic acid, making it a versatile and indispensable tool for high-yield automated synthesis and complex macromolecular assemblies.   ...

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Desoxyrhaponticin, a stilbene glycoside from rhubarb, is a potent BACE1 inhibitor with an IC50 value of 1.213µM.   Products are for research use only. Not for human use. We do not sell to patients.   Desoxyrhaponticin, a stilbene glycoside from rhubarb, is a potent BACE1 inhibitor with an IC50 value of 1.213µM [1]. Desoxyrhaponticin improves insulin resistance (IR) and reduces lipid accumulation through the PI3K/AKT/mTOR signaling pathway[2]. Desoxyrhaponticin is widely used as an internal standard to develop high-speed counter-current chromatography (HSCCC) methods for the large-scale separation and identification of related compounds[3].   In vitro, Desoxyrhaponticin treatment for 4 days significantly inhibited the ...

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VcMMAE is a drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs), consisting of the microtubule inhibitor monomethyl auristatin E (MMAE) and a cleavable valine-citrulline (vc) linker.   Products are for research use only. Not for human use. We do not sell to patients.   VcMMAE is a drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs), consisting of the microtubule inhibitor monomethyl auristatin E (MMAE) and a cleavable valine-citrulline (vc) linker[1-2]. In the ADC structure, VcMMAE is covalently linked to the antibody via the maleimide group of its linker. Upon specific cleavage by cancer cell lysosomes, VcMMAE releases ...

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FM1 43 is a water-soluble styryl dye with strong lipophilicity, and FM1-43 is widely used as a fluorescent membrane probe in biological research..   Products are for research use only. Not for human use. We do not sell to patients.   FM1-43 is a water-soluble styrene dye with strong lipophilicity. FM 1-43 membrane probe is a reagent that can specifically bind to cell membranes and inner membrane organelles to generate fluorescence.  FM1-43 is widely used as endocytosis and excision membrane structure markers, and can be used to identify actively firing neurons and research Mechanisms of activity-dependent vesicle cycling[1]. In actively ...

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